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Dr. Richa Misra

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Assistant Professor Department of Zoology richamisra@svc.ac.in

Educational Qualifications

  • Ph.D.

Areas of Specialization

  • Tuberculosis Biology, Human gut microbiome

Administrative roles/ responsibilities

    •	Co-opted member, Canteen committee, Sri Venkateswara college, 2018 onwards
    •	Member, IQAC/NAAC Criterion III compilation committee
    •	Member, Department AQAR compilation committee
    •	Member, Department workload and timetable committee
    •	Member, Zoology Society Evolvere
    •	Member, Department chemicals purchase committee
    •	Working group member in syllabus revision committee for B. Sc. (H) Biological Sciences papers: Core paper: Systems Physiology; DSE paper: Animal Behaviour and Chronobiology; SEC paper: Medical Diagnostics, 2019
    •	Convenor, International Webinar on “Rewilding Immunology: Current Status and the Road ahead” organized by the Department of Zoology, Sri Venkateswara College, University of Delhi, Delhi, 9th January, 2021.
    •	   Co-convenor, International Workshop on “Air Pollution and Public Health: Challenges and Interventions” organized by Sri Venkateswara College, University of Delhi and NAM S&T Centre, New Delhi, 5-7 Feb,2020.
    •	   Organizing Team Member in International Pre-conference workshop and e-Conference on "Health and Research in Current Scenario:with special emphasis on COVID-19 virus Genomics and Pathogenicity", jointly organized by Sri Venkateswara College, University of Delhi & PhiXgen Pvt. Ltd., India from 14-16th July and 17th July, 2020.
    •	   Organizing Co-secretary, Indo-US Symposium on Allergy and Asthma, AIIMS, Delhi, 15-16Dec, 2018.
    •	Research advisor in Prof. Yogendra Singh’s laboratory at Department of Zoology, University of Delhi to co-mentor 3 Ph.D. students.
    •	Reviewer of Scientific Reports, Plos One, PeerJ, Med Sci Monit, BioMed Research International, Infection and Drug Resistance, Heliyon

Courses Taught

  • B. Sc (H) Zoology (Physiology, Research Methodology, Chordates, Non-Chordates, Principles of Genetics, Evolutionary Biology, Medical Diagnostics, Biotechnology, Immunology); B. Sc (H) Biological Sciences (Systems Physiology, Biodiversity), B. Sc. Life Sciences (Immunology, Animal Biotechnology)
    1)	Singh A, Gaur M, Sharma V, Khanna P, Bothra A, Bhaduri A, Mondal AK, Dash D, Singh Y*, Misra R*. Comparative Genomic Analysis of Mycobacteriaceae Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the Mycobacterium tuberculosis Complex. mSystems. 2021 Jan 19;6(1):e00934-20. *Equal Corresponding doi: 10.1128/mSystems.00934-20. ISSN: 2379-5077, IF: 6.280
    2)	Gaur M, Singh A, Sharma V, Tandon G, Bothra A, Vasudeva A, Kedia S, Khanna A, Khanna V, Lohiya S, Varma-Basil M, Chaudhry A, Misra R*, Singh Y*. Diagnostic performance of non-invasive, stool-based molecular assays in patients with paucibacillary tuberculosis. Sci Rep. 2020 Apr 28;10(1):7102. *Equal Corresponding doi: 10.1038/s41598-020-63901-z. ISSN: 2045-2322, IF: 3.998
    3)	Singhal A, Virmani R, Naz S, Arora G, Gaur M, Kundu P, Sajid A, Misra R*, Dabla A, Kumar S, Nellissery J, Molle V, Gerth U, Swaroop A, Sharma K, Nandicoori VK, Singh Y. Methylation of two-component response regulator MtrA in mycobacteria negatively modulates its DNA binding and transcriptional activation. Biochem J. 2020 Dec 11;477(23):4473-4489. doi: 10.1042/BCJ20200455. ISSN: 1470-8728, IF: 4.097
    4)	Misra R, Menon D, Arora G, Virmani R, Gaur M, Naz S, Jaisinghani N, Bhaduri A, Bothra A, Maji A, Singhal A, Karwal P, Hentschker C, Becher D, Rao V, Nandicoori VK, Gandotra S, Singh Y. Tuning the Mycobacterium tuberculosis alternative sigma factor SigF through the multidomain regulator Rv1364c and osmosensory kinase, protein kinase D. J Bacteriol. 2019 Mar 13; 201(7). pii: e00725-18. doi: 10.1128/JB.00725-18, ISSN: 1098-5530, IF: 3.195
    5)	Gaur M, Vasudeva A, Singh A, Sharma V, Khurana H, Negi RK, Lee JK, Kalia VC, Misra R*, Singh Y*. Comparison of DNA Extraction Methods for Optimal Recovery of Metagenomic DNA from Human and Environmental Samples. Indian J Microbiol. 2019 Dec; 59(4): 482-489. *Equal Corresponding. doi: 10.1007/s12088-019-00832-y ISSN: 0046-8991, IF: 1.870
    6)	Virmani R, Sajid A, Singhal A, Gaur M, Joshi J, Bothra A, Garg R, Misra R, Singh VP, Molle V, Goel AK, Singh A, Kalia VC, Lee JK, Hasija Y, Arora G and Singh Y. The Ser/Thr protein kinase PrkC imprints phenotypic memory in Bacillus anthracis spores by phosphorylating the glycolytic enzyme enolase. J Biol Chem. 2019 May 31; 294(22): 8930-8941. doi: 10.1074/jbc.RA118.005424. ISSN: 0021-9258, IF: 4.190
    7)	Maji A§, Misra R§, Dhakan DB§, Gupta V, Mahato NK, Saxena R, Mittal P, Thukral N, Sharma E, Singh A, Virmani R, Gaur M, Singh H, Hasija Y, Arora G, Agrawal A, Chaudhry A, Khurana JP, Sharma VK, Lal R, Singh Y. Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers. Environ Microbiol. 2018 Jan;20(1):402-419. Equal Contribution. ISSN: 1462-2920, IF: 4.933
    8)	Maji A§, Misra R§, Mondal AK§, Bhatia S, Bajaj D, Singhal A, Arora G, Bhaduri A, Sajid A, Kumar D, Singh S, Singh H, Rao V, Dash D, Shalini B, Michael JS, Chaudhary A, Gokhale RS, Singh Y. Expression profiling of lymph nodes in tuberculosis patients reveal inflammatory milieu at site of infection. Sci Rep. 2015 Oct 15;5:15214. Equal Contribution. ISSN: 2045-2322, IF: 3.998
    9)	Grewal GK, Singh KD, Kanojia N, Rawat C, Kukal S, Jajodia A, Singhal A, Misra R, Nagamani S, Muthusamy K, Kukreti R. Exploring the carbamazepine interaction with human pregnane X receptor and effect on ABCC2 using in vitro and in silico approach.  Pharm Res. 2017 Jul;34(7):1444-1458. ISSN: 1573-904X, IF: 3.613
    10)	Biswas S, Sarkar A, Misra R. Iron affinity gel and gallium immobilized metal affinity chromatographic technique for phosphopeptide enrichment: a comparative study. Biotechnol. Biotechnol. Equip. 2017 Feb;31(3):639–646. ISSN: 1310-2818, IF: 1.15
    11)	Arora G, Misra R, Sajid S. Model systems for pulmonary infectious diseases: Paradigms of anthrax and tuberculosis. Curr Top Med Chem. 2017 17:1-23. ISSN: 1568-0266, IF: 3.335
    12)	Arora G, Sajid S, Virmani R, Singhal A, Kumar S, Dhasmana N, Khanna T, Maji A, Misra R, Molle V, Becher D, Gerth U, Mande S, Singh Y. Ser/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillus anthracis. NPJ Biofilms and Microbiomes. 2017. 3:7 ISSN: 2055-5008, IF: 7.576 
    13)	Saraav I, Pandey K, Misra R, Singh S, Sharma M, Sharma, S. Characterization of MymA protein as a flavin containing monooxygenase and as a target of isoniazid. Chem Biol Drug Des. 2017 Jan;89(1):152-160. ISSN: 1747-0285, IF: 2.596
    Book Chapters:
    1)	Understanding the Connect of Quorum Sensing and CRISPR-Cas System: Potential Role in Biotechnological Applications. A Singh, M Gaur and R Misra*. Quorum Sensing and its Biotechnological Applications, 2018, pp 231-247, Springer Nature Singapore. ISBN 978-981-13-0848-2 https://doi.org/10.1007/978-981-13-0848-2 
    2)	Tackling the Antibiotic Resistance: The “Gut” Feeling. Misra R*, Virmani R, Dhakan D, and Maji A. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer; 2017, pp 325-338, Springer International Publishing Switzerland. ISBN: 978-3-319-48682-6. DOI: 10.1007/978-3-319-48683-3_14 
    3)	Synthetic Solutions to Drug Resistance. Arora G, Misra R, and Sajid A. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer; 2017. pp 595-608. Springer International Publishing Switzerland. ISBN: 978-3-319-48682-6. DOI: 10.1007/978-3-319-48683-3_26 
    •	Interviewed for the Science & Technology section of the national newspaper “The Hindu” for article titled “How gut bacteria affect immunity” dated April 14, 2018 in recognition of the research work published in Environ Microbiol. 2018 Jan;20(1):402-419.
    •	Interviewed for my work on Extrapulmonary Tuberculosis for a report in Nature Medicine. Article:  Beyond the breath: Exploring sex differences in tuberculosis outside the lungs. Nat Med. 2017 Apr 7;23(4):398-401. doi: 10.1038/nm0417-398.
    •	Invited talk as Eminent speaker on Tuberculosis at International Conference on Natural products & Human Health organized by Deshbandhu College, 29th February, 2020.
    •	Invited lecture on ‘Tuberculosis & Gut microbiome’ at INSCR International conference (CTM2019), Oct 11-12, 2019, MDU Rohtak.
    •	Awarded with Bill and Melinda Gates Foundation Global Health Travel Award for participation in Keystone Symposia on Mycobacteria: Physiology, Metabolism and Pathogenesis, 2010