Ph.D (All India Institute of Medical Sciences, New Delhi)
M.Sc Biotechnology, Madurai Kamaraj University, Madurai, Chennai
Areas of Specialization
Infectious Diseases specifically Tuberculosis Pathophysiology, High throughput Transcriptomics and Proteomics, Bacterial Genetics, Regulation of Gene expression, Bacterial Signal Transduction Pathways, Molecular Biology and Recombinant DNA Technology
Administrative roles/ responsibilities
• Coordinator, SSR Department Report, Sri Venkateswara College, University of Delhi (2021)
• Member, NIRF Team, Sri Venkateswara College, University of Delhi (2018 - 2021).
• Convenor, “MindSpar 3.0 - Adding New Challenges” Ideathon event organized by the Department of Biochemistry, Sri Venkateswara College in collaboration with Regional Center for Biotechnology in Jan, 2021 (ongoing).
• Member, Department Research Committee, Department of Biochemistry, University of Delhi South Campus (2016-2020).
• Convenor/Incharge, Prospectus Committee, Sri Venkateswara College, University of Delhi to design the College Prospectus / Information bulletin for academic session 2015, 2016, 2017, 2019 and 2020.
• Teacher-in-Charge, Department of Biochemistry, SVC (20th May – 22nd July 2018) (23 July, 2019 to 25 May, 2020).
• Convenor, “Catalysis-The Biochemical Society”, Department of Biochemistry, Sri Venkateswara College (2019-2020).
• Core Committee Member for organizing VISTAAR - One day science popularization event funded under the CTEP-DBT program (November 1, 2019).
• Member, Working Committee to revise the syllabus of B.Sc (H) Biochemistry and B.Sc (H) Biological Sciences under CBCS (LOCF-UGC) (2019).
• Member of Committee to establish Satellite Incubator in SVC in collaboration with Acharya Narendra Dev College (2019-Present).
• (In place of TIC) Incharge, Department of Biochemistry, SVC (18 May 2019 to 6 July 2019).
• Member, Canteen Committee, SVC (2017-2019, 2019 to present).
• Member, Time-Table Committee, SVC (2017-2018).
• Member, Magazine Committee, SVC (2015-2017).
Courses Taught
• B.Sc (Hons) Biochemistry – 3 Year program (FYUP, Semester and CBCS mode)
• B.Sc (Hons) Biological Science – 3 Year program (FYUP, Semester and CBCS mode)
• Post Graduate Diploma in Molecular and Biochemical Technology –One Year program
Original Peer Reviewed Research Articles
• Hariharan, V.N., Yadav, R., Thakur, C., Singh, A., Gopinathan, R., Singh, D.P., Sankhe, G., Malhotra, V., Chandra, N., Bhatt, A. and Saini, D.K. Cyclic di-GMP sensing histidine kinase PdtaS controls mycobacterial adaptation to carbon sources (2021) FASEB J. https://doi.org/10.1096/fj.202002537RR
• Singh, K. K., Bhardwaj, N., Sankhe, G. D., Udaykumar, N., Singh, R., Malhotra, V., & Saini, D. K. (2019). Acetylation of Response Regulator Proteins, TcrX and MtrA in M. tuberculosis Tunes their Phosphotransfer Ability and Modulates Two-Component Signaling Crosstalk. Journal of molecular biology, 431(4), 777–793. https://doi.org/10.1016/j.jmb.2019.01.004
• Vashist, A.,* Malhotra, V., Sharma, G., Tyagi, J. S., & Clark-Curtiss, J. E. (2018). Interplay of PhoP and DevR response regulators defines expression of the dormancy regulon in virulent Mycobacterium tuberculosis. The Journal of biological chemistry, 293(42), 16413–16425. https://doi.org/10.1074/jbc.RA118.004331 (corresponding author and * equal first author contribution)
• Korch, S. B., Malhotra, V., Contreras, H., & Clark-Curtiss, J. E. (2015). Erratum to: The Mycobacterium tuberculosis relBE toxin: antitoxin genes are stress-responsive modules that regulate growth through translation inhibition. Journal of microbiology (Seoul, Korea), 53(12), 875. https://doi.org/10.1007/s12275-015-0741-3
• * Malhotra, V., Agrawal, R., Duncan, T. R., Saini, D. K., & Clark-Curtiss, J. E. (2015). Mycobacterium tuberculosis response regulators, DevR and NarL, interact in vivo and coregulate gene expression during aerobic nitrate metabolism. The Journal of biological chemistry, 290(13), 8294–8309. https://doi.org/10.1074/jbc.M114.591800 (corresponding author and * equal first author contribution)
Books/e-Lessons/Chapters
• Contributed two chapters in Life Science Protocol Manual. Department of Biotechnology, Govt of India. January 2018, ISBN No. 978-93-5300-545-0 Page numbers: 227-243; 145-148
• Editor for two topics in Life Science Protocol Manual. DBT. January 2018, ISBN No. 978-93-53000-545
• E-Lesson Plan (2018): Teaching about Microbial Life and Climate Change as a part of the project Trans disciplinary Research Oriented Pedagogy for Improving Climate Studies and Understanding (TROP ICSU) funded by International Council of Science available at https://tropicsu.org/lesson-plan-teaching-about-microbial-life-andclimate-change/
Awards
• 2015 - Bio-CARe Women Scientist Research Award by the Department of Biotechnology, Govt. of India
• 2016 - Global Heath Travel Award by the Bill and Melinda Gates Foundation and Keystone Symposia
• 2020 - Best Poster Prize at the ISW-2020 - International Summit on Women in STEM-“Visualizing the future: New Skylines held on January 23-24, 2020 at India Habitat Center, New Delhi organized by the Department of Biotechnology, Govt. of India and ICGEB, New Delhi
Educational Qualifications
Awards